sparsentan will reduce the level or influence of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep an eye on. Sparsentan (a CYP2C19 inducer) decreases publicity of CYP2C19 substrates and decreases efficacy associated with these substrates.Edgar and Seidel (1997) investigated the effects of modafinil on sleep-wake EEG and lo
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